ORIGINAL PAPER
The systemic immune-inflammation index and neutrophil-lymphocyte ratio in pediatric burned patients – a pilot study
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Institute of Medical Sciences, University of Opole, Opole, Poland
Submission date: 2022-07-25
Final revision date: 2022-10-06
Acceptance date: 2022-10-23
Publication date: 2023-03-21
Corresponding author
Agata Maria Kawalec
Agata Maria Kawalec, PhD, Institute of Medical Sciences, University of Opole, 48 Oleska St., 45-052 Opole, Poland
Pediatr Pol 2023;98(1):8-11
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ABSTRACT
Introduction:
The aim was to assess the usefulness of blood analytical markers such as systemic immune- inflammation index (SII) and neutrophil-lymphocyte ratio (NLR) in pediatric burned patients.
Material and methods:
The study group included 73 children (23 girls and 50 boys; mean age: 3.83; SD: 4.77; min–max: 0–17 years old) hospitalized due to burns. A retrospective analysis of selected complete blood cell count parameters (leucocytes; platelets – PLT; SII; NLR) collected on the day of injury and selected parameters of burns (extent, depth of the injury, duration of hospitalization, type of treatment) was performed.
Results:
Children with burns that exceeded 10% total body surface area had higher levels of leucocytes than children with less extensive burns (p = 0.023). The PLT count on the day of injury was higher in children with burn wounds that required surgical treatment (p = 0.021). The analysis of groups of children that differed in the values of NLR revealed that children with NLR over 3 were hospitalized longer (on average 3.5 days) than children whose NLR was lower than 3 (p = 0.048). It was found that children with SII over 250 were hospitalized longer than children with SII less than 250 (p = 0.019). There were no differences in the type of treatment (p = 0.21), but children with SII over 250 had more often full thickness burns (p = 0.036). Children under 2 years old with SII over 200 more often required surgical treatment than children with SII less than 200 (p = 0.005). Children under 2 years old with SII over 200 more often had full thickness burn wounds than children with SII less than 200 (p = 0.045). Children under 2 years old with NLR over 2 had more extensive burn wounds (p = 0.049) than children with NLR under 2.
Conclusions:
The systemic immune-inflammation index and NLR can be useful in assessment of pediatric patients with burns. Further studies on larger groups including children with major burns are necessary.
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