REVIEW PAPER
Saliva testing for Helicobacter pylori infection in children and adolescents – a literature review
1
Department of Developmental Age Medicine and Paediatric Nursing, Medical University of Bialystok, Bialystok, Poland
2
Department of Maxillofacial Surgery, University Clinical Hospital in Bialystok, Bialystok, Poland
3
Department of Pediatrics and Pulmonary Diseases, University Clinical Hospital in Bialystok, Bialystok, Poland
Submission date: 2019-05-30
Final revision date: 2019-07-29
Acceptance date: 2019-07-30
Publication date: 2019-08-30
Pediatr Pol 2019;94(4):255-258
KEYWORDS
TOPICS
ABSTRACT
Helicobacter pylori is known as one of the most common Gram-negative bacteria in the world. Infection takes place via oral-oral, gastro-oral, and faecal-oral routes. The oral-oral route is considered to be the most common route of transmission. The presence of H. pylori in the saliva is considered as a factor inducing periodontal disease and tooth decay, as well as changes such as aphthous ulcers, leucoplakia, and lichen planus. Furthermore, existing bacteria in dental plaques such as Streptococcus mutans and Prevotela intermedia may produce bacteriocins that promote the growth of H. pylori. Recent studies have focused on infection of H. pylori mainly in adults, although infection often occurs in early childhood. As such, more studies concerning the developmental population are needed. Saliva, as an easily available biological material, may soon become an important source in the diagnosis of H. pylori infections, especially in children and adolescents.
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