ORIGINAL PAPER
Physicians’ awareness concerning primary immunodeficiencies in the Ternopil Region of Ukraine
Submission date: 2018-02-06
Final revision date: 2018-04-24
Acceptance date: 2018-04-24
Publication date: 2018-07-20
Pediatr Pol 2018;93(3):221-228
KEYWORDS
TOPICS
ABSTRACT
Introduction:
Primary immunodeficiencies (PID) are genetic defects of the immune system that result in chronic, serious, and often life-threatening infections if they are not diagnosed and treated. Worldwide, from 70 to 90% of PID sufferers remain undiagnosed because of poor awareness. Early diagnosis is very important for adequate prevention and management of PID infectious complications and may improve the life quality of patients with PID.
Aim of the study:
The aim of this study was to assess the awareness of physicians of different specialties about the signs of primary immunodeficiency in children and adults.
Material and Methods:
A survey among physicians of different specialties on awareness of PID was conducted. The study involved physicians of the Ternopil region of Ukraine. Of 103 participants 42 were paediatricians, 25 general practitioners/family physicians, eight internists, 13 paediatric surgical specialists, and 15 physicians of paediatric sub-specialties. The survey consisted of a questionnaire containing 25 questions.
Results:
Sixty-one (59.2%) physicians gave more than 50% of correct answers. The percentage of correct answers to the questions about warning signs of PID in children was 66.1% among paediatricians and 64% among general practitioners, in adults – 66.7% and 72%, respectively. The lowest knowledge of PID was about the specific signs of PID, more often concerning verification of Nijmegen breakage syndrome, ataxia-telangiectasia, and DiGeorge syndrome.
Conclusions:
This study has revealed poor awareness about PID among physicians in the Ternopil region of Ukraine. There was no significant difference in the percentages of correct answers among the first-contact physicians (paediatricians, general practitioners/family physicians) and paediatric sub-specialists. There is a significant need for educational programs to improve physicians’ knowledge on PID. Implementation of the model of combined physician education and public awareness may improve detection of PID in children in the early stages.
Primary immunodeficiencies (PID) are genetic defects of the immune system that result in chronic, serious, and often life-threatening infections if they are not diagnosed and treated. Worldwide, from 70 to 90% of PID sufferers remain undiagnosed because of poor awareness. Early diagnosis is very important for adequate prevention and management of PID infectious complications and may improve the life quality of patients with PID.
Aim of the study:
The aim of this study was to assess the awareness of physicians of different specialties about the signs of primary immunodeficiency in children and adults.
Material and Methods:
A survey among physicians of different specialties on awareness of PID was conducted. The study involved physicians of the Ternopil region of Ukraine. Of 103 participants 42 were paediatricians, 25 general practitioners/family physicians, eight internists, 13 paediatric surgical specialists, and 15 physicians of paediatric sub-specialties. The survey consisted of a questionnaire containing 25 questions.
Results:
Sixty-one (59.2%) physicians gave more than 50% of correct answers. The percentage of correct answers to the questions about warning signs of PID in children was 66.1% among paediatricians and 64% among general practitioners, in adults – 66.7% and 72%, respectively. The lowest knowledge of PID was about the specific signs of PID, more often concerning verification of Nijmegen breakage syndrome, ataxia-telangiectasia, and DiGeorge syndrome.
Conclusions:
This study has revealed poor awareness about PID among physicians in the Ternopil region of Ukraine. There was no significant difference in the percentages of correct answers among the first-contact physicians (paediatricians, general practitioners/family physicians) and paediatric sub-specialists. There is a significant need for educational programs to improve physicians’ knowledge on PID. Implementation of the model of combined physician education and public awareness may improve detection of PID in children in the early stages.
REFERENCES (21)
1.
Modell V, Knaus M, Modell F, et al. Global overview of primary immunodeficiencies: a report from Jeffrey Modell Centers worldwide focused on diagnosis, treatment, and discovery. Immunol Res 2014; 60: 132-144.
2.
Bousfiha AA, Jeddane L, Ailal F, et al. Primary immunodeficiency diseases worldwide: more common than generally thought. J Clin Immunol 2013; 33: 1-7.
3.
Espinosa-Rosales FJ, Condino-Neto A, Franco JL, et al. Into action: Improving access to optimum care for all primary immunodeficiency patients. J Clin Immunol 2016; 36: 415-417.
4.
Modell F, Puente D, Modell V. From genotype to phenotype. Further studies measuring the impact of a Physician Education and Public Awareness Campaign on early diagnosis and management of primary immunodeficiencies. Immunol Res 2009; 44: 132-149.
5.
Chernyshova LI, Bondarenko AV, Kostyuchenko LV, et al. Epidemiology of primary immunodeficiencies in Ukraine according to the register of patients. Child’s Health 2015; 7: 16-23.
6.
Kinash M, Dmytrash L, Dzyuban L, et al. Structure of Primary Immunodeficiencies in Ternopil Region of Ukraine. Centr Eur J Immunol 2014; 39: 14.
7.
Joshi AY, Iyer VN, Hagan JB, et al. Incidence and temporal trends of primary immunodeficiency: a population-based cohort study. Mayo Clin Proc 2009; 84: 16-22.
8.
Dantas ED, Aranda CS, Nobre FA, et al. Medical awareness concerning primary immunodeficiency diseases in the city of São Paulo, Brazil. Einstein (Sao Paulo) 2013; 11: 479-485.
9.
Dantas EO, Arandaa CS, Rego Silva AM, et al. Doctors’ awareness concerning primary immunodeficiencies in Brazil. Allergol Immunopathol (Madr) 2015; 43: 272-278.
10.
Nourijelyani K, Aghamohammadi A, Salehi Sadaghiani M, et al. Physicians awareness on primary immunodeficiency disorders in Iran. Iran J Allergy Asthma Immunol 2012; 11: 57-64.
11.
Al-Hammadi S, Al-Reyami E, Al-Remeithi S, et al. Attentiveness of paediatricians to primary immunodeficiency disorders. BMC Res Notes 2012; 5: 393.
12.
Yuksek M, Ikinciogullari A, Dogu F, et al. Primary immune deficiency disease awareness among a group of Turkish physicians. Turk J Pediatr 2010; 52: 372-377.
13.
Hernandez-Trujillo VP, Scalchunes C, Hernandez-Trujillo HS, et al. Primary Immunodeficiency Diseases: An Opportunity in Pediatrics for Improving Patient Outcomes. Clin Pediatr (Phila) 2015; 54: 1265-1275.
14.
Adeli M, Hendaus M, Imam L, Alhammadi A. The importance of educating paediatricians about primary immunodeficiency disorders: a tertiary hospital experience. Georgian Medical News 2015; 246: 66-72.
15.
Orange JS, Seeborg FO, Boyle M, et al. Family Physician Perspectives on Primary Immunodeficiency Diseases. Front Med (Lausanne) 2016; 30: 12.
16.
Orange JS, Seeborg FO, Boyle M, et al. Pulmonologist perspectives regarding diagnosis and management of primary immunodeficiency diseases. Allergy Asthma Proc 2016; 37: 162-168.
17.
Lewandowicz-Uszynska A, Szaflarska A, Pietrucha B, Tarnowska I. Educational program for doctors and nurses taking care for primary Immunodeficiency patients treated with subcutaneous immunoglobulins. Pol Merkur Lekarski 2011; 30: 452-457.
18.
Subbarayan A, Colarusso G, Hughes SM, et al. Clinical Features that Identify Children with Primary Immunodeficiency. Pediatrics 2011; 127: 810-817.
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