CASE REPORT
Nasopharyngeal carcinoma in a six-year-old female child: a case report
Submission date: 2019-01-26
Final revision date: 2019-03-04
Acceptance date: 2019-03-04
Publication date: 2019-04-29
Pediatr Pol 2019;94(2):132-135
KEYWORDS
TOPICS
ABSTRACT
Nasopharyngeal carcinoma (NPC) is an extremely rare malignancy among the paediatric age group. The relative rarity of paediatric NPC makes the diagnosis difficult. Consequently, NPC tends to be locally advanced at the time of diagnosis in the paediatric age group and is sometimes associated with distant metastasis. The diagnosis of paediatric NPC should prompt immediate treatment. We report a case of undifferentiated nasopharyngeal carcinoma in a young girl who presented with advanced loco-regional disease and was treated with chemoradiation.
REFERENCES (14)
1.
Sun LM, Li CI, Huang EY, Vaughan TL. Survival differences by race in nasopharyngeal carcinoma. Am J Epidemiol 2007; 165: 271-278.
2.
Kao WC, Chen JS, Yen CJ. Advanced nasopharyngeal carcinoma in children. J Cancer Res Pract 2016; 3: 84-88.
3.
Chang ET, Adami HO. The enigmatic epidemiology of nasopharyngeal carcinoma. Cancer Epidemiol Biomarkers Prev 2006; 15: 1765-1777.
4.
Pastore G, De Salvo GL, Bisogno G, et al. Evaluating the access to pediatric cancer care centers of children and adolescents with rare tumors in Italy: the TREP project. Pediatr Blood Cancer 2009; 53: 152-155.
5.
Lo KW, To KF, Huang DP. Focus on nasopharyngeal carcinoma. Cancer Cell 2004; 5: 423-428.
7.
Sultan I, Casanova M, Ferrari A, et al. Differential features of nasopharyngeal carcinoma in children and adults: a SEER study. Pediatr Blood Cancer 2010; 55: 279-284.
8.
Zhang L, Chen QY, Liu H, et al. Emerging treatment options for nasopharyngeal carcinoma. Drug Des Devel Ther 2013; 7: 37-52.
9.
Afqir S, Ismaili N, Alaoui K, et al. Nasopharyngeal carcinoma in adolescents: a retrospective review of 42 patients. Eur Arch Otorhinolaryngol 2009; 266: 1767-1773.
10.
Youssef AA, Raafat TA. Nasopharyngeal carcinoma: Imaging features of unusual cancer in children. Egypt J Radiol Nucl Med 2015; 46: 943-947.
11.
Lu S, Wei J, Sun F, et al. Late Sequelae of Childhood and Adolescent Nasopharyngeal Carcinoma Survivors After Radiation Therapy. Int J Radiat Oncol Biol Phys 2019; 103: 45-51.
12.
DeRenzo C, Lam C, Rodriguez‐Galindo C, et al. Salvage regimens for pediatric patients with relapsed nasopharyngeal carcinoma. Pediatr Blood Cancer 2019; 66: e27469.
13.
Patel PN, Penn EB. Presentation and management of nasopharyngeal carcinoma, a rare childhood malignancy. Int J Pediatr Otorhinolaryngol Extra 2016; 14: 20-22.
14.
Huang Y, Zhang J, He Q, et al. Clinical outcome and prognostic analysis of young adults nasopharyngeal carcinoma patients of a nonendemic area in intensity-modulated radiotherapy era. Future Oncol 2019; 15: 381-389.
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