Introduction:
The literature describes an association between a positive family history of allergic diseases and the incidence of allergies in children. Aim: The aim of the study was to evaluate the influence of the family history of allergy on the incidence of hyper-sensitivity to food in infants exclusively breastfed up to 6 months of age.

Materials and methods:
The study involved 106 infants exclusively breastfed up to 6 months of age, in whom due to atopic eczema and/ or symptoms of gastrointestinal tract allergy tests were conducted. The family history includes allergies with immediate family members, parents and siblings. All the patients were diagnosed for IgE-mediated and non-IgE-mediated food allergy. The statistical analysis was performed.

Results:
In infants with positive allergy test results (n = 84), 34 patients (40.5%) were affected by the family history of allergic diseases. In the group with IgE-mediated sensitization, family history of allergic diseases affected 50.0%; in children with non-IgE-mediated hypersensitivity to food - 39.7%; in children with the mixed type - 42.9%. In the group of patients who did not show hypersensitivity to the allergens examined, family history of atopy affected 36.4% of infants. In our study, in infants exclusively breastfed up to 6 months of age there was no association between the prevalence of hypersensitivity to food and the family history of atopy.

Conclusion:
On the basis of own research results and reports of other authors it can be assumed that genetic factors are not significant in the develop¬ment of non-IgE-mediated hypersensitivity to food in young children.